Peptide-Phosphorodiamidate Morpholino Oligomers (PMO)
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WuXi TIDES provides Phosphorodiamidate Morpholino Oligomers (PMO) process development and manufacturing services from pre-clinical to commercial in Changzhou, China, the same site as our peptide CMC teams. Leveraging our know-how together with our proprietary (patented) solid support, cleavage and deprotection process as well as customized reactors, we can manufacture PMO efficiently from gram scale to multi-kilogram scale with high quality.
Leveraging our peptide manufacturing from one site in Changzhou, China, WuXi TIDES can also produce peptide-PMO (PPMO) with streamlined process. PMO and PPMO development and manufacturing are supported by our in-house comprehensive analytical, project management, as well as CMC regulatory teams. To date, we have completed dozens of PMO projects including 10+ PPMO projects.
Case Study: Streamlined peptide-PMO development and manufacture
- Seamless collaboration with in-parallel activities across 6 teams
- Integrated CMC approach enables IND filing in 11 months
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